Optn Polyclonal Antibody for Rat(Rattus norvegicus) | EIAab.comOptn Polyclonal Antibody for Rat(Rattus norvegicus)

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Optn (Gene name),

Optineurin (Protein name ), OPTN_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Optn;

Protein name:

Optineurin;

Alternative:

FIP-2-like protein;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with HD. Interacts with Rab8 (RAB8A and/or RAB8B). Interacts with transcription factor IIIA (GTF3A). Interacts with TRAF3, TBK1 and MYO6. Binds to ubiquitin.

Function:

Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8. Links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation. Plays a neuroprotective role in the eye and optic nerve. Probably part of the TNF-alpha signaling pathway that can shift the equilibrium toward induction of cell death. May act by regulating membrane trafficking and cellular morphogenesis via a complex that contains Rab8 and hungtingtin (HD).

Subcellular Location:

Cytoplasm perinuclear region Golgi apparatus Golgi apparatus trans-Golgi network Found in the perinuclear region and associates with the Golgi apparatus. Colocalizes with MYO6 and RAB8 at the Golgi complex and in vesicular structures close to the plasma membrane.

Protein Attributes:

Sequence length:

585

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

585:

HGQQPRSIPI | HSCPKCGEVL | PDIDTLQIHV | MDCII

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.63435

STRING:

10116.ENSRNOP00000045795

String:

Q8R5M4

Pfam:

PF11577

KEGG:

rno:246294

Uniprot:

Q8R5M4

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ELISA Kit for Rat Optineurin

Cat.:

E15443h

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Packing:

96T

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ELISA Kit for Rat Optineurin

Cat.:

E15443c

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Packing:

96T

ELISA Kit for Rat Optineurin

Cat.:

E15443m

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96T

ELISA Kit for Rat Optineurin

Cat.:

E15443p

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96T

ELISA Kit for Rat Optineurin

Cat.:

E15443r

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96T

CLIA Kit for Rat Optineurin

Cat.:

U15443r

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96T

CLIA Kit for Rat Optineurin

Cat.:

U15443c

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Packing:

96T

CLIA Kit for Rat Optineurin

Cat.:

U15443m

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MSDS:

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Packing:

96T

CLIA Kit for Rat Optineurin

Cat.:

U15443h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat Optineurin

Cat.:

U15443p

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat Optineurin

Cat.:

P15443Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Optineurin

Cat.:

P15443Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Optineurin

Cat.:

P15443Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Optineurin

Protein for Rat Optineurin

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Identification of genes expressed in rat injured dental pulp."
Myokai F. , Oyama M.
Submitted (2001-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue: Testis.

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